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MCAT Biology - 60 Essential Concepts

Prepare for MCAT Biology with 60 high-yield concepts covering all major topics tested on the biological sciences section.

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Front

What is the primary function of the nucleolus?

Back

Synthesis of ribosomal RNA (rRNA) Tip: The nucleolus is a non-membrane bound structure within the nucleus where ribosome assembly begins.

Front

Which organelle is responsible for lipid synthesis and detoxification?

Back

Smooth Endoplasmic Reticulum (SER) Tip: Contrast this with the Rough ER, which is studded with ribosomes for protein synthesis.

Front

What is the primary function of lysosomes?

Back

Hydrolytic breakdown of macromolecules Tip: Lysosomes maintain an acidic pH (~5) to optimize enzyme activity.

Front

How are mitochondria inherited in humans?

Back

Maternally (Cytoplasmic inheritance) Tip: Mitochondrial DNA is circular and replicates independently of the nucleus.

Front

Which cytoskeletal component is composed of actin and involved in cytokinesis?

Back

Microfilaments Tip: Microfilaments form the cleavage furrow during cell division.

Front

What is the structural arrangement of microtubules in cilia and flagella?

Back

9 + 2 arrangement Tip: This consists of nine pairs of microtubules surrounding two central microtubules.

Front

Which organelle modifies, sorts, and packages proteins into vesicles?

Back

Golgi Apparatus Tip: Think of the Golgi as the 'Post Office' of the cell.

Front

What is the role of peroxisomes in the cell?

Back

Breakdown of very long chain fatty acids via beta-oxidation Tip: They produce hydrogen peroxide (H2O2) as a byproduct.

Front

During which phase of the cell cycle does DNA replication occur?

Back

S phase (Synthesis) Tip: The cell enters S phase only after passing the G1 restriction point.

Front

What occurs during Prophase I of meiosis that increases genetic diversity?

Back

Crossing over (Recombination) Tip: This occurs between homologous chromosomes at the chiasmata.

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