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Pharmacology Drug Classes - 50 Essentials

Learn 50 essential pharmacology drug classes with mechanisms, indications, and key side effects.

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ACE Inhibitors (e.g., Lisinopril)

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Inhibit ACE to prevent Angiotensin II formation Indicated for HTN and HF; side effects include dry cough and hyperkalemia.

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Beta-Blockers (e.g., Metoprolol)

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Antagonize beta-adrenergic receptors Used for HTN and arrhythmias; side effects include bradycardia and fatigue.

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Calcium Channel Blockers (Dihydropyridines)

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Inhibit L-type calcium channels in vascular smooth muscle Used for HTN and angina; side effects include peripheral edema and flushing.

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Statins (HMG-CoA Reductase Inhibitors)

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Inhibit HMG-CoA reductase to lower cholesterol Indicated for hyperlipidemia; side effects include myalgia and liver enzyme elevation.

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Loop Diuretics (e.g., Furosemide)

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Inhibit Na-K-2Cl symporter in the thick ascending limb Used for edema and HF; side effects include hypokalemia and ototoxicity.

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Thiazide Diuretics (e.g., Hydrochlorothiazide)

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Inhibit Na-Cl transporter in the distal convoluted tubule First-line for HTN; side effects include hypokalemia and hyperuricemia.

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Angiotensin II Receptor Blockers (ARBs)

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Block AT1 receptors directly Used for HTN when ACE inhibitors cause cough; side effects include hyperkalemia.

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Cardiac Glycosides (Digoxin)

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Inhibit Na+/K+-ATPase pump Used for HF and Atrial Fibrillation; side effects include yellow-green halos and arrhythmias.

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Nitrates (Nitroglycerin)

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Increase cGMP to cause venous vasodilation Indicated for acute angina; side effects include headache and orthostatic hypotension.

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Antiplatelets (Clopidogrel)

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Irreversibly block P2Y12 ADP receptors Used to prevent MI and stroke; side effects include bleeding and dyspepsia.

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